Tramadol 50mg - Hydrocodone | Is It Useful For Post Operative Pains?

[PharmaRxOnline]

Yes it is both the pain relievers Tramadol & Hydrocodone are useful for moderate to severe pain. Generally both are effective pain killers but Tramadol is more impactful in giving severe pain relief than that of Hydrocodone.

Tramadol vs Hydrocodone: Which one is better?

Tramadol and Hydrocodone are two painkillers that are used to reduce pain which is not easily retrieved from any other pain killers. Both painkillers can treat moderate to severe pain after surgery or in chronic conditions such as cancer. However, for many cases of pain, non-opioid therapy is usually tried first.

Both Tramadol and Hydrocodone work by binding to mu opioid receptors to change how a person responds to pain. As prescription opioid, they are more potent than your average over-the-counter pain reliever. Therefore, these drugs require a visit with a doctor to assess your pain.

What are the main differences between Tramadol and Hydrocodone?

Tramadol is the generic name for Ultram, Ultram ER, ConZip, and many more. It is a Schedule IV class C narcotic according to the DEA which means it has some potential for abuse. While it binds to opioid receptors, it can also increase the activity of other brain neurotransmitters such as nor epinephrine and serotonin.

Hydrocodone is the generic name for Zohydro ER and Hysingla ER. Hydrocodone is also taken as a combination tablet with acetaminophen under the brand names Vicodin or Lortab. Unlike Tramadol, Hydrocodone is a Schedule II DEA controlled medication which has a higher risk of abuse.

Is Tramadol or Hydrocodone more effective?

Tramadol and Hydrocodone are both effective prescription opioid for pain. There are several studies comparing their effectiveness. Because Hydrocodone is a Schedule II opiate, it may be considered more potent although it comes with a higher potential for abuse. Tramadol may have a lower abuse potential as well as milder side effects.

In one multicenter study, Tramadol with acetaminophen was compared with Hydrocodone with acetaminophen in patients experiencing pain from an ankle sprain. Around 400 patients were split into two groups receiving one drug or the other. Results found that both medications provide comparable pain relief within four hours versus placebo.

In another clinical trial, Hydrocodone with acetaminophen was compared with Tramadol in 68 patients. These patients had arrived at an emergency department for musculoskeletal pain in their joints, bones, or muscles. A result found that hydrocodone with acetaminophen provides more pain relief compared to Tramadol based on pain scores with a visual analog scale (VAS).

In a double-blind trial, Hydrocodone with acetaminophen was compared to Tramadol in 118 patients with chronic pain from cancer. Tramadol showed pain relief in 62% of patients compared to 56.5% of patients with Hydrocodone. However, pain relief was similar in both groups. Tramadol was also found to produce milder side effects versus Hydrocodone.
Whether you are prescribed Tramadol or Hydrocodone is highly dependent on the level of your pain. When assessing your pain, your doctor will look at your complete medical history, any history of substance abuse, and any medications that could cause drug interactions. Therefore, pain medications are highly individualized and require a doctor’s consultation to determine which will be more effective for you.

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