Future of Chromatography Resins: Innovations Shaping the Separation Industry

[Animesh Rao]

The chromatography resin market size is projected to reach USD 4.1 billion by 2028 from USD 2.8 billion in 2023, at a CAGR of 8.2%. The report offers key projections on critical factors such as chromatography resin market size, production, revenue, consumption, CAGR, gross margin, and pricing. Increasing pharmaceutical and biopharmaceutical R&D activities are projected to drive the demand for chromatography resins market. However, the lack of enough trained experts is limiting the growth of the market. In contrast, the growing need for disposable pre-packed columns has created opportunities for manufacturers.

The rising demand for therapeutic antibodies is the main driver behind the growth in the industry. Major pharmaceutical companies are actively engaged in the research and development of therapeutic antibodies. One crucial step in purifying monoclonal antibodies involves the removal of anionic impurities like nucleic acids and endotoxins using anion exchange chromatography. Therefore, the crucial role of chromatography techniques in the advancement of monoclonal antibodies is anticipated to propel the chromatography resin market.

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Chromatography Resin Companies

Bio-Rad Laboratories Inc. (US), Merck KGaA (Germany), Danaher Corporation (US), Tosoh Corporation (Japan), Bio-Works Technologies AB (Sweden), Avantor Performance Materials, Inc. (US), Mitsubishi Chemical Corporation (Japan), among others are the major players in this market.

Bio-Rad Laboratories, Inc. is a multinational manufacturer and worldwide distributor of life science research and clinical diagnostics products. Life science, clinical diagnostics, and others are the three reportable business segments through which it conducts its business activities. Chromatography resins are offered by the business through its life science division. Through subsidiaries with an emphasis on sales, customer support, and product distribution, the company has direct distribution channels in over 35 countries outside of the US. Distributors and agents in some regions outside and inside of these 35 countries, such as North America, South America, Latin America, Europe, and Asia Pacific, improve sales efforts. The acquisition of Celsee, Inc., a provider of tools and supplies for the isolation, detection, and analysis of single cells, was announced by the company in April 2020. It is expected that Celsee's innovative goods and technologies will increase Bio-Rad's presence in the quickly expanding fields of precision medicine and single-cell analysis, both of which provide a better understanding of disease, diagnosis, and treatment.

The Danaher Corporation is a multinational conglomerate with headquarters in the US that develops, produces, and sells professional, medical, industrial, and commercial goods and services. The three reportable segments that Danaher Corporation uses to run its operations are life sciences, diagnostics, and environmental & applied solutions. Through Cytiva, a recently acquired independent business, Danaher provides chromatography resins. The company has operations in 40 countries and territories, including the Middle East, North and Latin America, Asia, and Europe. In order to accelerate the ramp-up of production, Solis BioDyne turned to Danaher in April 2021. Solis BioDyne is a manufacturer of molecular biology applications, including tools for analyzing human DNA, and as such, is a participant in COVID-19 testing. At the Testa Center in Uppsala, Sweden, Solis BioDyne placed its newfound manufacturing skills into effect and helped Danaher grow its affinity chromatography resin product line.

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Pharmaceutical & Biotechnology is estimated to be the fastest-growing application of the chromatography resin market in terms of value during the forecast period.

The growth of the abovementioned segment can be attributed to various key factors. These factors include an increase in research and development activities focusing on therapeutic areas like cancer, HIV/AIDS, and immunodeficiency disorders. Technological advancements in biotechnology research and the emphasis placed by pharmaceutical and biotechnology companies on expanding their product pipelines also contribute to the growth. The rising number of drug discovery and clinical trial projects, as well as the expiration of patents for blockbuster drugs and biomolecules, further drive the segment's expansion. Moreover, the availability of funding from both government and corporate sources for biotechnology and pharmaceutical research plays a significant role. The growth of the pharmaceutical industry as a whole and the presence of strict regulatory guidelines for drug development and safety act as additional driving factors for this segment's growth.

Asia Pacific is projected to be the fastest-growing market for chromatography resin during the forecast period.

The Asia Pacific region is expected to experience significant market growth, making it the fastest-growing market in terms of value during the forecast period. Many leading pharmaceutical companies are establishing research and development centers in these countries due to the economic advantages and the presence of skilled professionals. The increasing focus on food safety and growing investments in pharmaceutical and life science research are contributing to the rising demand for chromatography resin in this region.