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Prescription painkillers are powerful drugs that interfere with the nervous system’s transmission of the nerve signals we perceive as pain. Most painkillers also stimulate portions of the brain associated with pleasure. Thus, in addition to blocking pain, they produce a “high.”

The most powerful prescription painkillers are called opioids, which are opium-like1 compounds. They are manufactured to react on the nervous system in the same way as drugs derived from the opium poppy, like heroin. The most commonly abused opioid painkillers include desoxyn, hydrocodone, ephreridine, hydromorphone and Mophine , Xanax.

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